Mind Lab Pro Review SummaryMind Lab Pro is without doubt the most comprehensive nootropic on the market right now. It delivers an awesome combination of effective, powerful nootropics. Each ingredient has been thoroughly tested in clinical trials – in every case, Opti Nutra have chosen the best ingredient to get the job done. Mind Lab Pro enhances focus, increases learning capacity, reduces stress, promotes neurogenesis, and protects the brain from oxidative stress. This is total brain optimization. What more could you want from a nootropic? -VISIT THE MIND LAB PRO WEBSITE- Mind Lab Pro Review: What can this nootropic do?If you have spent any amount of time researching nootropics online, the you’ve 100% come across Mind Lab Pro before now. This stack is one of the most recognisable nootropics in the world. It is regularly listed as one of the best stacks around; biohackers and professionals from the supplement industry overwhelmingly give Mind Lab Pro reviews a near perfect score for potency, value for money, and safety. But are these Mind Lab Pro reviews to be believed? What does Mind Lab Pro do exactly? If you look at the official website, you’ll see that Mind Lab Pro is a full-spectrum, complete nootropic supplement. It claims to deliver:
That is one comprehensive list of benefits! This might actually be the most ambitious nootropic on the market today. There are few products that even come close to offering this many benefits. Here is a visual representation of how Opti Nutra see Mind Lab Pro working:
If this actually plays out in reality, then Mind Lab Pro will be the total package. So, does it? Does Mind Lab Pro really work? Is it safe? Should you worry about side effects? Is there a better supplement for increasing cognitive function than Mind Lab Pro? We answer all of these questions and more in our Mind Lab Pro review, which you can find below. Enjoy! Mind Lab Pro ingredientsWhat is in Mind Lab Pro exactly? This is the most important question Mind Lab Pro reviews needs to answer. So let’s take a look at the formula in some detail. Here is the Mind Lab Pro ingredients list, as it is shown on the bottle: Here is a list of all of the ingredients in Mind Lab Pro in case that image isn’t clear:
That is one top quality formula. We’re already impressed with the diversity of ingredients and the generous doses. We’ll now give you a brief overview of what each ingredient does, how it contributes to enhanced cognitive performance, and what we make of the dose. Citicoline (as Cognizin) – 250mgCiticoline is probably our favorite cholinergic. It is without doubt one of the most efficient and effective ways to raise acetylcholine levels in the brain. As it is the brain’s primary executive neurotransmitter, increasing acetylcholine is the best way to rapidly increase focus, accelerate information processing, enhance short-term memory function, and improve all-round cognitive performance. Citicoline has other benefits too – it promotes healthy brain cell membrane formation. Mind Lab Pro gives us 250mg of top quality Citicoline. Cognizin is a standardized, branded form of Citicoline. It is the gold standard for this ingredient. 250mg of Cognizin will definitely give you noticeable improvements in focus and learning. Bacopa monnieri (9 bioactive bacosides) – 150mgBacopa monnieri is – in our opinion – the most effective natural memory-enhancer in existence. Supplementing with bacopa monnieri has been shown in numerous different clinical trials to be effective for improving memory retention, recall accuracy, and recall speed. Some studies have even found that it improves memory test performance among older people struggling with age-related memory loss. Mind Lab Pro contains a unique bacopa monnieri extract. They have extracted the 9 bioactive bacosides which contribute to better memory function in humans. So unlike the whole plant Bacopa monnieri powders you see in most nootropics, Mind Lab Pro gives you as much of the good stuff as possible. Lion’s Mane Mushroom – 500mgLion’s Mane Mushroom consumption stimulates the release of Nerve Growth Factor (NGF) in the brain. NGF is one of the most important neurotrophic factors in the human brain. It regulates the growth, differentiation, maturation, and repair of neurons. To put things simply, having higher NGF levels in the brain means your neurons are repairing faster, they’re proliferating (increasing in number), and they are maturing much more quickly. We don’t need to tell you what the long-term effects of having higher NGF levels might be. Studies have found that repeated, regular supplementation with Lion’s Mane Mushroom greatly improves multiple different aspects of cognitive function. Mind Lab Pro provides 500mg of full spectrum Lion’s Mane extract. Phosphatidylserine – 100mgPhosphatidylserine is a phospholipid. It is a structural component of brain cell membranes. In fact, it is a primary structural component; a staggeringly large proportion of your brain cell membranes are phosphatidylserine. It is also necessary for healthy brain cell signalling. When a brain cell reaches the end of its life, phosphatidylserine moves to the outside of the membrane. This acts as a signal for immune cells to come and kill the dying, poorly functioning cell. Phosphatidylserine is an extremely important substance for healthy brain function. Sadly, phosphatidylserine levels naturally decline as we age. We do consume some through food, but if you want to maximize cognitive performance, supplementing is necessary. You don’t need much – 100mg per day is plenty! N-Acetyl L-Tyrosine – 175mgTyrosine is amino acid with immense nootropic potential. It is starting to appear in more and more nootropics as the manufacturers wake up to Tyrosine’s full capabilities. Tyrosine supplementation has been found to dramatically improve cognitive function in people subjected to extreme stress. For example, one clinical trial found that Tyrosine supplementation improved mental performance in people who were sleep deprived. Another found that it enhanced focus, learning and memory function in people subjected to extreme cold. Tyrosine is therefore the perfect choice for athletes, students, or busy professionals looking to maximize productivity during busy periods. Mind Lab Pro gives you 175mg of highly bio-available N-Acetyl L-Tyrosine. This is within the idela dose range of 150-300mg. L-Theanine – 100mgTheanine is a great addition to a daily nootropic stack. Its main purpose is to counter the most severe side effects of caffeine. Theanine actually works synergistically with caffeine – it heightens its best, most beneficial effects while taking the edge off the jitteriness and anxiety that comes from drinking too much coffee. Theanine also promotes a calm, relaxed mind and induces sleep when consumed in large doses at night. Theanine is also an amino acid. It is found in relatively high concentrations in black tea. But even then, the total amounts are small. To really get any benefit from theanine, you kind of need to supplement a concentrated powder form. The 100mg we get from Mind Lab Pro should work well with your morning cup of coffee, producing a clear, energetic but calm mind. Rhodiola rosea (3%, 1% extract) – 50mgIf we had to make one complaint about Mind Lab Pro, it’s that it doesn’t contain enough Rhodiola rosea. We are big fans of this natural anxiolytic. Rhodiola rosea is one of the best natural substances for reducing anxiety and alleviating the physical symptoms of stress. It works quickly, lowering blood pressure, reducing muscle tension, and promoting a calm, clear mind. When coupled with other anxiolytics like Tyrosine or Ashwagandha, Rhodiola rosea becomes even more effective. One thing we like about Rhodiola rosea is the fact that it seems to work extremely well for everybody. It isn’t just effective in people suffering with severe anxiety – 50-150mg per day will benefit everybody. Maritime Pine Bark (95% proanthocyanidins) – 75mgThis is one of the ingredients that really sets Mind Lab Pro apart from the competition. Maritime Pine Bark is a potent natural source of antioxidants. But not just any antioxidants. The proanthocyanidins found in Maritime Pine Bark are specifically suited to protecting brain cell health. These potent antioxidants readily cross the blood brain barrier while simultaneously promoting healthy brain blood flow. This means they are perfect for promoting long term brain cell health. Mind Lab Pro delivers 75mg of extremely high potency Maritime Pine Bark Extract. The extract Opti Nutra have used here is practically pure antioxidants. You’ll struggle to find a nootropic stack which takes brain cell health more seriously! -Visit MindLabPro.com To Learn More-Our Thoughts On The Mind Lab Pro FormulaThere’s no two ways to say it – Mind Lab Pro is the most comprehensive, balanced nootropic formula on the market today. For a daily, long-term brain supplement, we don’t see how Opti Nutra could have done much better here. Mind Lab Pro covers every aspect of cognitive performance. The Citicoline rapidly increases focus and processing speeds, while the Bacopa monnieri enhanced memory retention, recall, and formation speed. Rhodiola rosea and Tyrosine work together to keep you calm and thinking clearly during times of serious mental and physical strain. While all this is going on, the Lion’s Mane Mushroom is at work stimulating new brain cell growth. This, coupled with the protective effects of the Maritime Pine Bark and the structural support of phosphatidylserine, will lead to a dramatically more powerful, healthier brain over the long-term. What’s most impressive is the lack of waste in Mind Lab Pro. Opti Nutra have showed serous restraint here. The temptation is often to fill your stack with as many ingredients as you can – often, this means you get several unnecessary ingredients (increasing side effect risks and jacking up the price). Mind Lab Pro is the complete package, but it doesn’t go overboard – everything has a job, and every facet of cognitive performance is taken care of, but there’s no excess at all. No bloat. No padding. Just proven, effective brain supplements. Mind Lab Pro is, in many ways, the perfect daily nootropic stack. It enhances multiple different aspects of cognition. It has both short, medium, and long-term effects. It is extremely safe and should be completely side effect-free for 99.9% of users. If you are just looking for a supplement to give you a short-lived energy and focus kick, then there are better options than Mind Lab Pro, like caffeine. But if you want a nootropic which delivers total brain optimization, this is definitely the product for you. Check out the website to learn more about the formula -> MindLabPro.com. Editor’s Notes: My experiences with Mind Lab ProI first came across Mind Lab Pro a few years ago. At the time, I was bitterly disappointed with the state of the nootropics market. There were some good products, but most of the top selling brain supplements were cheap rip-offs or outright scams. Even the reputable stacks available at the time used proprietary blends and useless filler ingredients. So, I was excited when Opti Nutra brought out a full-spectrum, comprehensive brain supplement offering total formula transparency and extensive scientific backing. I began taking Mind Lab Pro as soon as my first 4 bottles arrived (3 days after ordering). Immediately, I noticed a small but measurable increase in focus, concentration, and productivity. I found that I was able to stay focused on my work for long, unbroken periods. The more complicated aspects of my work seemed easier, and I was able to finish my morning’s work by 11am – an hour earlier than usual. After about 2 weeks of using Mind Lab Pro every day, there was no doubting it – I was operating at a higher level of cognition. I was able to process information very quickly, my memory was significantly better, and my productivity levels had increased dramatically. One of the biggest differences for me was the reduction in stress levels I experienced over the course of the first 4 weeks. Normally, I find that as my workload increases, my stress levels increase too. But while using Mind Lab Pro, I actually felt much calmer despite having an unusually busy period of deadlines to deal with. After 8 straight weeks of using Mind Lab Pro on a daily basis, I was ready to make this my regular nootropic stack. To seal the deal, I carried out my usual range of cognitive tests (the same tests I use on every nootropic, before and after using them). As I expected, the Bacopa monnieri and Lion’s Mane Mushroom had brought about major improvements in memory function. My scores on several different recall and memorization tests were far better after 8 weeks of using Mind Lab Pro compared to before I began. I finished the experiment after 12 weeks to see how long the benefits lingered and to take stock of what I’d learned. Not only did I not experience any side effects during the entire 12 weeks, but I also enjoyed the benefits for a good couple of weeks after I stopped the trial. This is something I can’t say for many other products on the market today. All-in-all, a top quality brain supplement. Mind Lab Pro remains my daily nootropic stack of choice. I take it every single day. It is the foundation of my supplement regimen. It is by far and away the best natural nootropic supplement I have ever used, and I’ve used a lot of them! I recommend this brain supplement to anybody who wants an all-in-one, comprehensive nootropic. If you want a single nootropic which covers all the most important bases, without causing any side effects, and without costing you hundreds of dollars, then I strongly advise you to give Mind Lab Pro a try.
This account was written by our Editor, Brian Johnson. He stresses that anecdotal data is not conclusive. What works for one person will not work for everyone. But in his extensive experience using nootropics over the years, he feels he is well placed to know a great supplement when he tries one.
Testimonials & User Reviews: What are people saying about Mind Lab Pro?We don’t put a lot of stock in anecdotal reports. But when reviewing nootropics – or any supplements – it’s worth looking at what other people have been saying about them. This is especially true when a supplement has the backing of industry professionals (rather than just celebrities). This is another area where Mind Lab Pro stands out. Here are a range of Mind Lab Pro reviews from notable figures in various professions and sports:
https://youtu.be/5RIPRU87QzE
https://youtu.be/XvWxJa8gTZc
https://youtu.be/g6EJjqXwQ4k
You cannot always believe everything third parties say about a product. They might not be lying necessarily; they just might not understand the product, and they might be failing to account for other factors. But in this case, we have testimonials from genuine leaders in their respective fields. That’s the kind of testimonial it is hard to argue with. You can read more of these stories from the Mind Lab Pro stories page, which you can find here. Side Effects: Is Mind Lab Pro safe?Is Mind Lab Pro safe? Will it cause side effects? We’re happy to say that Mind Lab Pro is a safe nootropic supplement. Our team of reviewers have all used Mind Lab Pro themselves; some continue to take it on a daily basis. None of them have ever experienced any side effects whatsoever while using Mind Lab Pro. More importantly, the clinical data suggests that the chances of experiencing side effects while using this nootropic are very low. Every ingredient in Mind Lab Pro has been tested in multiple clinical trials. None of them have been found to pose significant side effect risks. At the doses used here, side effects of any kind of extremely rare. When they do occur, they are mild and transient.
Of course, everyone is different. Some of you may respond badly to certain herbal extracts which do not cause any problems for most people. If you do experience any side effects while using Mind Lab Pro, discontinue use as talk to your doctor asap.
Please remember that we are not doctors and that this is not medical advice. We don’t know anything about you or your medical history. You must do your own research thoroughly and talk to a qualified medical professional before using any nootropics – even if they look as safe as Mind Lab Pro!
If you have any concerns whatsoever, get in touch with the manufacturer directly and get their opinion -> MindLabPro.com. Mind Lab Pro Review Conclusion: Is this the best nootropic?We’re extremely impressed with Mind Lab Pro. We think everybody would benefit immensely from using this nootropic. As a daily brain supplement, it can’t be beaten. It is extremely comprehensive, covering every aspect of cognitive performance. It improves focus, learning capacity, and memory function in the short-term. At the same time, it promotes long-term brain cell growth. Few stacks combine such immediate benefits with brain adaptation support. Mind Lab Pro does it perfectly. If you’re looking for a supplement to give you a quick but transient boost in focus, energy and concentration, then there are stacks better suited to you. Mind Lab Pro offers total brain optimization. If you’re looking for a supplement to help you enhance every aspect of your mental performance – focus, memory, stress resistance, brain cell proliferation, brain cell health, and so on – then we don’t see how you could do better than Mind Lab Pro. If you are looking for a simpler, more economical option that you can more easily stack with other supplements, maybe check out Performance Lab Mind. It is a kind of stripped down version of Mind Lab Pro, but we actually prefer it. But if you want the full package, we strongly recommend giving Mind Lab Pro a try. You wont regret it! It is the best complete, all-in-one nootropic on the market. Visit the website to find out more: -Visit MindLabPro.com-Via https://www.vagarights.com/mind-lab-pro-review/
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Modafinil is increasingly being used as a nootropic treatment for Attention Deficit Hyperactivity Disorder (ADHD), as well as for a growing range of related conditions. Those of you who are familiar with Modafinil as a medical drug might be surprised by this. Originally designed for narcolepsy and other sleeping disorders, Modafinil is first and foremost a wakefulness promoting agent. As a eugeroic, it helps keep people awake for prolonged periods without acting as a classic psychostimulant. But those of you with experience using Modafinil as a cognitive enhancer will know that this drug could potentially be great for people with ADHD. Few drugs give you the same laser-like focus and motivation as Modafinil, and it certainly doesn’t struggle to keep you alert and attentive. In this article, we’re going to look at Modafinil as a treatment for ADHD symptoms. We’ll look at how effective modafinil is for ADHD, how it might work for people with no ADHD diagnosis, and how it compares to other ADHD medications. How Is ADHD Diagnosed?ADHD was once thought to be a childhood condition that disappeared as the child got older. This is however not true. Recent research suggests that adult ADHD is more common than we realize. Adult ADHD prevalence in the United States is currently 4.4%. ADHD can also be linked to other mental disorders. ADHD sufferers are more likely to experience anxiety and depression [2]. A higher incidence of substance abuse is also common in ADHD patients. ADHD is not a condition. ADHD is a behavioral condition that can cause problems with focus and attention. ADHD can cause you to be unable to concentrate on one task at a time. ADHD can also cause difficulty following through with your plans, and you may have difficulty focusing on what is important. This is a serious problem that is growing and affects many people. ADHD is a condition that affects approximately 9.4% of American school-aged children. What are the causes of ADHD?ADHD is a common disorder that affects the perception and processing of people’s behavior. ADHD is characterised by persistent patterns of hyperactivity and inattention that disrupt daily life. Although the cause of ADHD remains elusive, scientists have discovered that genetics, environment, and brain chemical makeup all play a part in the development of the disorder . ADHD can be diagnosed at any age, but it is most commonly diagnosed in childhood. It can also be found in adult cases in certain cases. It can be difficult to pinpoint a cause and it is possible that multiple factors are involved. There are many possible causes for ADHD.
Neurochemical Causes of ADHDThere is a lot of debate over the precise causes of ADHD, as is clear from the section above. But on a most basic level, we do know that ADHD is at least characterized – if not caused – by disruptions in the function of neurotransmitters. Specifically, dopamine and norepinephrine appear to be dysregulated in most cases of ADHD. We know that these neurotransmitters in particular are causing the most noticeable symptoms of ADHD because these are the neurotransmitters most affected by the stimulant-based ADHD medications known to be most effective. This is precisely why Modafinil has had so much interest as a potential ADHD treatment. Modafinil acts as a dopamine reuptake inhibitor and as a broader eugeroic, which means it excites the CNS but without the same kind of jittery effects or any sort of “high”. In other words, on a neurochemical level, Modafinil appears to do exactly what Adderall does but in a safer, less side effect causing way! So, does Modafinil work for ADHD? How does it compare to other ADHD medications? Modafinil vs. other ADHD MedicationsModafinil is a novel wakefulness-promoting agent which is used to treat excessive sleepiness. It has been shown to be more effective in treating ADHD in children and adults. Modafinil’s brain mechanism of action is still not completely understood. However, it is believed to increase the dopamine levels in certain brain areas. Modafinil is structurally different to other dopaminergic stimulants, and it has a lower risk of abuse. Modafinil is approved to treat ADHD in children 6 years old and older. It has been shown to improve executive function and cognition in children with ADHD. Modafinil and ADHD: Side Effects and BenefitsWhen it comes to ADHD treatment, there is no one-size fits all solution. ADHD sufferers may respond well to medication while others may find behavioral therapy more beneficial. Some people find that combining therapy and medication is the best combination. Modafinil is a medication that can be used to treat ADHD. It has the following benefits: Improved focus, concentration, motivation [8]. Modafinil may also be used to reduce impulsivity or hyperactivity. Modafinil can cause headaches, nausea, anxiety, insomnia, and other side effects. Most side effects are mild and disappear within a few days. Is Modafinil a good option for ADHD?Many people suffering from ADHD find Modafinil helps to focus. Modafinil is not a cure for ADHD but can be used to manage certain symptoms. Modafinil can also be used to treat other conditions like narcolepsy and sleep apnea. Modafinil is an effective medication for ADHD. There are many benefits to Modafinil. It is an effective medication. It’s also safe and has no severe side effects. Modafinil has a half-life of 15 hours, whereas Adderall can last 9-14 hours. If you don’t know about Modafinil, it can cause insomnia. Is there any ADHD drug interaction with ModafinilModafinil is a popular treatment for ADHD. It is increasingly used as an alternative to Adderall since it is porbably the closest thing to Adderall you can use without actually using other amphetamine-based drugs. Some people have trouble with Modafinil if they take other medications at the same time. It is important to be aware that Modafinil can cause hypersensitivity reactions in people who are already taking ADHD medications. Modafinil may cause hypersensitivity reactions to other medications and can have serious side effects. It is crucial to inform your doctor about all medications that you take, including any medication you are taking for ADHD. Conclusion: Can you use Modafinil to treat ADHD?The simple answer is yes, you can use Modafinil for ADHD symptoms. Many clinical practitioners prescribe Modafinil (typically as Provigil or Nuvigil) to their ADHD patients when more typical drugs such as Adderall, Concerta or Vyvanse are not proving effective. In cases where side effects prohibit the use of stimulant-based medications, Modafinil can be the perfect solution for treating ADHD. Modafinil is a eugeroic, which means it excites the CNS but does not have the typical psychoactive effects of classic stimulant drugs. If you do not have an ADHD diagnosis, Modafinil is likely going to be extremely effective at helping you stay focused and motivated for hours on end. If you don’t have ADHD, Modafinil can keep you awake for up to 8 hours without you feeling tired in the slightest. For those 8 hours you will also feel incredibly motivated, focused and driven to be productive. Via https://www.vagarights.com/modafinil-adhd/ People with ADHD have trouble directing their attention. Because of this, they often notice things other people don’t. This can lead to strange associations. People with ADHD also tend to be highly passionate about something and tend to focus more on it than most people. This is another reason why ADHD and creativity go hand in hand. In this article, we’re going to look at the link between ADHD and creativity. We will look at how ADHD might make people more creative, and in what areas of artistic creation they are more likely to excel. Does ADHD make you creative?The answer to the question, “Does ADHD make you creative?” depends on the person. For example, people with ADHD tend to have more creative ideas than people without ADHD. They can sidestep the conventional thinking process and use their creativity to solve problems. In addition, people with ADHD tend to be more impulsive, which can result in greater creative output. One study found that individuals with ADHD have higher creative abilities in the mechanical/scientific, artistic, and performance domains. However, enhanced performance during the early stages of creative problem solving may not be sufficient to predict increased real-world creativity. ADHD participants were more likely to choose fewer original and useful problem reconstructions than non-ADHD individuals. Moreover, subjects with ADHD showed lower levels of self-esteem. Another study looked at the creativity levels of adults with ADHD and those without. In this study, participants were asked to come up with novel uses for a set of objects. Participants with ADHD and those without ADHD generated about the same number of ideas. Their creativeness wasn’t affected by their medication, but those with ADHD were more likely to generate ideas if they were rewarded with a bonus. This suggests that rewards and competition may be beneficial motivational factors. How would an ADHD brain be more creative?ADHD patients often have a distinct advantage when it comes to tasks that require creative thinking. They have trouble holding themselves back, and their mind wanders, which often results in a new idea. This type of creativity is not limited to cognitive thinking, but can also include a more artistic side. Many studies have found that ADHD patients can be extremely creative. They have the ability to create works of art and invent new products. In addition to this, people with ADHD are often hyper-focused. They may work on assignments without noticing that they’re doing it, and it may even be possible for them to do so in a shorter time. Researchers have also found that people with ADHD are better at creative cognition, a set of mental processes that promote divergent thinking, conceptual expansion, and overcoming knowledge constraints. In a recent study published in the Journal of Creative Behaviour, ADHD participants were asked to think up names for an alien fruit, and the results showed that their alien fruit and product names were much more creative than those produced by control subjects. Dopamine and creativityIn a new study, researchers have found a link between dopamine and creativity. They found that patients treated with dopaminergic drugs had enhanced verbal and visual creativity. These effects were independent of the patients’ ICD diagnosis. The researchers suggest that dopaminergic drugs act by reducing latent inhibition. This may result in enhanced divergent thinking. Dopamine is a neurotransmitter that has many functions. In particular, it is linked to divergent and convergent thinking. The level of dopamine in the brain is related to individual performance. In the study, individuals with a higher EBR had greater divergent thinking than those with lower EBR. Dopamine is important for creativity. High levels of the chemical improve attention switching, which is essential for successful creative performance. However, too much dopamine can impair cognitive functions like working memory, critical thinking, and reflection. It is also known to affect mood and motivation. Are ADHD people more imaginative?A recent study reveals that people with ADHD are especially good at creative cognition, a set of mental processes that involves divergent thinking, conceptual expansion, and overcoming knowledge constraints. For example, researchers asked participants to imagine an alien fruit, then had them come up with a product name. The results indicated that ADHD participants were more creative than control subjects, producing alien fruit that diverged further from earthly fruits and conformed less to task examples. The researchers found that people with ADHD reported higher levels of creativity in the artistic, mechanical/scientific, and performance domains. However, the results are not conclusive because the creative abilities reported by ADHD patients are based on self-reports. Furthermore, the subjective judgment of creativity is influenced by the participant’s self-esteem, which is usually low in people with ADHD. Despite the findings, people with ADHD are still often considered to be more creative and innovative than the average person. While creative abilities vary among ADHD people, the research has consistently demonstrated that these individuals have a unique talent for innovation. Many successful entrepreneurs and other high-profile creatives have ADHD. Examples include Jamie Oliver and Richard Branson. Branson, the founder of Virgin, and Oliver, the world-famous chef. ADHD, Art and Creativity: What does the scientific research say?In one large-scale meta-analysis, 31 studies were reviewed on ADHD and creativity. This is defined as the ability of generating new and useful ideas. Previous research has suggested that ADHD is associated with creativity. The studies reviewed examined three main aspects of creativity: divergent thinking, which refers to imagining many different potential solutions to one problem with different possible solutions; convergent thinking, which refers to more formalized problem-solving processes, such as following sets of rules or instructions and finding the best answer to the problem; and finally, regular, everyday creative thinking or activities. Of those 31 studies, twenty-two studies looked at both ADHD and divergent thinking. Studies with children showed that divergent thinking was associated with ADHD symptoms, but not those diagnosed with ADHD. Research with adults was mixed with some showing higher divergent thinking in ADHD patients, while others did not show any differences. Six studies were reviewed to assess ADHD and convergent thought. Results showed either no improvement in creativity for ADHD children or negative results for ADHD adults. In addition, six studies of everyday creative abilities and creative achievement in people with ADHD were analyzed.The majority of these studies showed a clear positive correlation between ADHD and creative achievements in daily life for adults. The review shows that ADHD symptoms may be more severe in those with divergent thought than in those with ADHD. This suggests that ADHD-related impairments may be worsened by divergent thinking. This review shows that ADHD is not related to convergent thought and that individuals with ADHD may be more creative in real life. There were only a few studies included in the paper, and most of them had small sample sizes. Future research will require larger study samples and comparable measures to measure creativity across studies. Studies in the past have not found a link between creativity, ADHD, or any other mental disorders. Two studies were presented in this paper that looked at motivation as a possibility to explain the mixed results. The first study involved 71 participants with ADHD completing an activity that required them to generate ideas (think of new ways to use a newspaper and fork), a task that required them construct a problem (read about a problem and define it), and a questionnaire regarding creative accomplishments in daily life. Participants with ADHD had greater real-life achievements than those without ADHD, but they did not perform better on the tasks. Individuals with ADHD had greater motivation, but their motivation levels were not different between the two groups. Researchers examined whether people with ADHD performed better in creativity tasks that offered a chance to win a reward and whether creativity levels varied depending on what area was being measured. 45 participants with ADHD and 44 without ADHD participated in a divergent thinking task. This task required them to think of new uses for towels, books, tin cans, belts, and sometimes it was competitive for a reward. Participants also completed a questionnaire measuring creativity in five different areas: artistic, mechanical/scientific, performance, scholarly, and self/everyday. Research showed that ADHD adults were more creative when they had to compete for a reward than those without ADHD. For those with ADHD, creativity was not affected by the competitive nature of the task. Compared to those without ADHD, individuals with ADHD also reported being more creative in the specific areas of mechanical and scientific creativity. These findings show that ADHD adults are more creative and have higher motivation to win rewards. It is possible that ADHD individuals may also be more creative in their everyday lives. Results suggest that ADHD adults may be more creative in real-world areas they enjoy, which could be more rewarding for them as a result. Conclusion: Does ADHD make people more creative?Are people with ADHD more creative? The simple answer to this question is no, ADHD itself does not necessarily make people more creative. However, there are ways that ADHD may foster original, creative ways of thinking and promote the kind of artistic expression we associate with creative genius. The fact of the matter is, ADHD changes the way the brain joins thoughts together. A distracted, wandering mind is not a productive one, but it can be a creative one. In the right context, and importantly if the person is interested in an idea or problem, ADHD can be a huge boon for creativity. Via https://www.vagarights.com/adhd-creativity/ Vitamins and ADHD medication have a strong relationship. Those of you who have read our other learning resources on Adderall will know that the drug is known to interact with nutrients such as magnesium, L-Tyrosine and caffeine, to name just a few. So what about Vitamin C? Is Adderall made less effective by Vitamin C? Vitamin C, whether in food or as a supplement to vitamin A, can reduce the effectiveness of Adderall. This applies to all forms of Adderall, including generics, name brands, extended-release and instant releases. It is alsotrue of Adderall alternatives like Vyvanse, Focalin, Concerta and Ritalin. However, this does not necessarily mean that you want to completely avoid vitamin C while you’re on Adderall. Let’s now look at how Adderall interacts and interacts with vitamin C and try to decide if it is a good or bad interaction. Vitamin C and AdderallIt is best to avoid Vitamin C for at least one hour before and after you take medication. This is because Adderall, which is alkaline, is more acidic than Vitamin C. Vitamin C can act as an “off-switch” to Adderall, affecting the body’s absorption rate. This means that you will need to be very careful about what you eat. Avoid foods and drinks that are high in Vitamin C, such as oranges, bell peppers and guavas, during your Adderall dose. These foods should be scheduled for later in the day or earlier, and at least one hour before or after taking your Adderall. Don’t be afraid to take Vitamin C even if it interacts with Adderall. This is because your body needs VitaminC to maintain healthy connective tissue and keep your immune system working properly. Vitamin C For Adderall ComdownYou’ll feel the withdrawal effects slowly diminishing as you stop taking Adderall. You might feel like you are going through withdrawal. You may feel tired or have intense emotions. These effects can be severe. However, increasing your Vitamin C intake can help reduce withdrawal symptoms. Vitamin C, as we have already mentioned, can reverse Adderall’s effects. Vitamin C can help to stop Adderall from lingering in your system, thereby allowing withdrawal to be completed sooner. Vitamin C and Catecholamine synththesisAnother big benefit of taking Vitamin C with Adderall is that the vitamin supports the healthy production of catecholamine neurotransmitters such as serotonin and dopamine. This is crucial, as chronic Adderall use is known to deplete levels of these neurotransmitters and to downregulate receptors over the long-term. Vitamin C Function in the Mind: Vital Role for the Ascorbate Transmitter (SVCT2 1 ) Ascorbate’s non-antioxidant activities in the brain and neural-derived tissues are centered on neurotransmitters. It is known that ascorbate is an essential co-factor in dopamine bhydroxylase’s conversion of dopamine into norepinephrine [123-124]. A series of elegant studies by many groups revealed a novel mechanism that involves ascorbate in order to transfer electrons across chromaffingranule membrane. According to the authors, Infusions intraventricular and striatal of ascorbate also reduced the behavioral effects of amphetamine. Ascorbate had similar results to that of haloperidol, a dopamine receptor antagonist. However, when the two agents were combined, they produced greater effects. The body tends to eliminate amphetamine more quickly when it becomes acidic (low pH). Conversely, Adderall clearance slows down in a pH-low environment. Vitamin C can acidify the urine which may promote the clearance of Adderall. Vitamin C can help to eliminate amphetamine residue in the kidneys and accelerate its elimination from the body. This is why I have been using Vitamin C at night to combat Adderall-related sleeplessness. Amphetamines and Oxidative StressThe brain is more likely to experience oxidative stress from amphetamine. High doses of amphetamine can cause neurotoxic. However, low-dose amphetamine is safe. Vitamin C may be an antioxidant that can help to prevent amphetamine-induced neurotoxicity. The following vitamins, nutraceuticals, and supplements can also protect the brain from the effects of Adderall:
A few studies support the idea that vitamin C might reduce the effects of amphetamine. Conclusion: Can you take Adderall and Vitamin C together?
It is interesting to see the connection between Adderall, vitamins and minerals. Vitamin C is one example of a vitamin that can make Adderall less effective. To reduce ADHD symptoms, you can also take Adderall along with other vitamins and minerals such as Zinc and Vitamin D. It is best to avoid eating foods high in Vitamin C close to the time you take Adderall. Also, increase your intake of vitamins and minerals to replenish any nutrients that are missing. Via https://www.vagarights.com/adderall-vitamin-c/ In the United States right now, around 6 million children aged 2-17 have been diagnosed with some form of Attention Deficit Hyperactivity Disorder (ADHD). Of those, over half (62%) are on some kind of ADHD medication: usually it is either Adderall, Concerta, Ritalin or Vyvanse. Despite ADHD being so prevalent, there is often very little discussion about dosing. Doctors will generally start everybody on the same standard dose of Adderall, Concerta or Vyvanse. They will then increase this steadily over time as the patient inevitably builds a tolerance to their ADHD medication. We think a lot of people are taking an ADHD medication dose that is far too high for their needs. This means they are being exposed to side effects unnecessarily, and they are paying for drugs they don’t really need (in terms of dosages). In this article, we’re going to look at the signs that your ADHD medication dose is too high. If you have experience lowering your Adderall dose to good effect, please share it with us in the comments. 10 Signs that your ADHD medication dosage and treatment is too highHere are eight indicators that your ADHD medication dosage is too high: #1. You Feel Tired All Day Long and feel like you have a Physical DependenceYour ADHD medication dosage may be too high if you feel tired all week. This could happen if you take too many medications or don’t adjust your dose properly. Talk to your doctor to adjust your dosage. #2. You Find Yourself Getting Angry EasilyYour ADHD medication dosage may be too high if you feel easily irritable, angry, or frustrated. This could happen if you take too many medications or don’t adjust the dose properly. Discuss this with your doctor right away. #3.You can’t concentrate in class or at workYour ADHD medication dosage might be too high if you have trouble concentrating, focusing, or paying attention. This can happen if you take too many of the drug or don’t adjust your dosage correctly. Talk to your doctor about lowering the dose. #4.You feel constantly stressed and uptightYour ADHD medication dosage could be too high if you feel anxious, stressed, or worried. This can happen if you take too many, don’t adjust your dosage correctly, or if you stop taking your medication altogether. Talk to your doctor. #5.You have insomnia/trouble falling asleepYour ADHD medication dosage should be decreased if you are experiencing insomnia, frequent awakenings, or difficulty sleeping. These symptoms can occur if your medication dose is too high or if you don’t adjust it correctly. Ask your doctor for guidance. #6.You feel more anxious than normalAnother side effect of too many medications is anxiety. ADHD sufferers often experience social phobia, obsessive-compulsive disorder, panic attacks and depression. These conditions can be made worse by medication. If you have ADHD symptoms, talk to your doctor to reduce your medication dosage. #7.You feel nauseous shortly after taking your ADHD medicationOne of the most common side effects to ADHD medication is nausea. People may experience dizziness, vomiting, diarrhea, constipation and dry mouth. Talk to your doctor immediately if you have any of these symptoms. Your doctor can adjust the dosage of your ADHD medication to address these issues. #8.The ADHD medication significantly changes your behaviorPeople who are taking ADHD medication claim they have trouble controlling their behavior. They can become impulsive or irritable. This is another indication that your ADHD medication dosage is too high. Talk to your doctor to reduce your medication. #9. You experience a “comedown” when your ADHD medication wears offIf you experience a kind of comedown or hangover once your ADHD medication wears off, then it is highly likely that your dosage is too high. People who take too much Adderall, Concerta or Ritalin typically find that they feel awful once the drug starts to leave their system, whereas an optimal dose shouldn’t produce this side effect. #10. You crave your next dose of Adderall, Concerta or VyvanseIf you find yourself looking forward to – or even craving – your next dose of Adderall, Concerta, Vyvanse or any other ADHD medication, then your dosage is likely to be far too high. Taking elevated doses of these ADHD drugs for prolonged periods can cause a kind of creeping dependency and addiction in some users. Signs of ADHD Medication OverdoseThere are two types of Adderall overdose symptoms: mild and severe. Some mild symptoms include:
These side effects aren’t serious and do not necessarily mean that you have taken too much Adderall. These minor side effects should be reported to your doctor so that you can adjust your dosage. Signs of a severe or acute Adderall overdose are immediately apparent and include seizures, fainting, blurred vision, shortness of breath and a pounding heart. If you have any of these symptoms it is vital that you get medical attention immediately. These symptoms will be the same for any stimulant-based ADHD medication overdoses. How much Adderall does it take to overdose?It is impossible to predict how much Adderall will be required to cause an overdose. Factors like:
You should only use Adderall if you have a prescription. Then, only take the medication exactly how it is prescribed. How can I tell if my Adderall dosage is too low for adults?It is important to determine if your medication for attention deficit hyperactivity disorder (ADHD) is working well enough to control your symptoms. This can be done by tracking your symptoms over time. You can do this by taking the Attention Deficit Hyperactivity Disorder Self-Assessment (ASDA). This questionnaire will help you identify ADHD-related behaviors and allow you to track your progress while you adjust your medication. The ASDA is divided into three sections. Section A questions you about your behavior and other problems. Sections B, C and D ask about your thoughts and feelings. Each section contains five questions, each of which addresses a specific ADHD symptom. The first section asks about impulsiveness and the second about concentration problems. The ASDA can be completed online or printed. You will receive feedback on your responses after you have completed the assessment. Your score will show the severity of your symptoms. This allows you to compare your current functioning with your past levels. A high score means that you have severe symptoms that require more treatment. A lower score means that your symptoms may be milder or less frequent. Zero indicates that you have no symptoms. Signs your Adderall prescription is too low:
Your doctor can increase your ADHD medication if your prescription is genuinely too low. Do I have the correct Adult ADHD medication?You may have been diagnosed with attention deficit hyperactivity disorder (ADHD) and know how difficult it can be to find the right drug for you. It’s possible to wonder if you are getting the best treatment for your needs and if there are any drugs that don’t work as well as others. There are many medications that can be used to treat ADHD. Each one has its own pros and cons. Here are some things you should consider before you decide to start taking prescription ADHD medication. How can I select the best ADHD medication?When choosing the right medication to treat ADHD, there are many factors you should consider. Before prescribing long-term treatment, your doctor may want to give you a trial period. This will allow you to test the medication’s effectiveness in your body. Titration is a gradual increase in the dosage of medication and monitoring your response. Your doctor will monitor your behavior and function to determine if there have been any changes. Your doctor may recommend that you continue the medication until the dosage is correct. What are my options for ADHD medication?There are many effective treatment options for ADHD. These include behavioral therapies like cognitive behavioral therapy (CBT), diet modifications, exercise, sleep hygiene, and behavioral therapies like CBT. However, natural remedies may also be available that can provide relief without side effects. To treat ADHD symptoms, some people turn to nutritional supplements such as vitamin B6, omega 3 fatty acid, magnesium, zinc, L-theanine, and vitamin B6. Some people turn to herbal remedies such as valerian root and chamomile tea. Others may turn to complementary therapies such as yoga, meditation and massage, chiropractic care, aromatherapy, and acupuncture to heal their bodies. What are the risks of ADHD medication?There are no known side effects associated with ADHD medication. However, there have been some side effects. These side effects include dizziness, nausea, vomiting, stomach upset, dizziness and headaches. These side effects are usually mild and resolve once the medication has started to work. How do you determine your first dose of ADHD medication?When deciding how much medicine to give you, a doctor will consider many factors. These factors include:
When determining the right starting dose, doctors will take into account each patient’s unique situation. When determining the best starting dose, doctors will consider your age, medical history and severity of ADHD symptoms. It is important to find the right dosage for you, while minimizing side effects. Insomnia is the most common side effect caused by methylphenidate, also known as Ritalin. Too high doses can cause insomnia. Talk to your doctor if you experience this. Side effects that could occur include nausea, vomiting, stomach upset, dizziness and dry mouth. Via https://www.vagarights.com/signs-adhd-medication-dose-too-high/ 9-Me-BC is one of those compounds that we have delayed reviewing for no good reason. It is probably one of the more popular of the nootropic research chemicals commonly used by biohackers and nootropics enthusiasts today. There has been a lot of discussion about 9-Me-BC on nootropics forums (mostly Reddit) in the last few months, so we thought it was time we did a proper analysis of the compound so you know everything you need to know before you consider using it. Is 9-Me-BC a good nootropic? Is it a good choice for a daily cognitive enhancer? Is 9-Me-BC safe? What are the side effects like? Can you even buy it legally over the counter? In this article, we’re going to answer all of these questions and more. We will look at what 9-Me-BC is, how it works, its side effects, and where you can buy it online. If you have personal experiences with this compound, please let us know in the comments how it worked for you. What is 9-MeBC? The compound 9-MeBC has potent cognitive-enhancing properties. It is part of a group of drugs known as dopaminergic, which are drugs that increase dopamine activity in the brain. An increase in dopamine activity or levels can translate into increased alertness, mood improvement, and spatial learning. These properties are why some people consider using it to enhance their cognitive abilities. This substance isn’t well-known by most “smart drugs” users because it isn’t mainstream. It is thought to function in a similar way to other mainstream nootropics like modafinil and armodafinil. It regulates brain levels of serotonin and dopamine (GABA), according to researchers. These chemicals have been shown to affect alertness, mood, wake-sleep cycles, and alertness. 9-MeBC is a new nootropic. Studies are currently being done to find out more about its safety and benefits. It is being investigated as a potential treatment for Parkinson’s Disease. 9-MeBC Active Compounds9-MeBC’s main ingredient is beta-carboline (b–carboline). It is a member of a group of carbolines found naturally in the brain, blood, meats, fruits and coffee. B-carboline is well known for its antioxidant properties and ability to affect brain function. How Does 9-Me-BC Work?A 2012 rodent study revealed that the nootropic stimulates neuron growth and increases dopamine levels in brains. After about 10 days, the drug’s effects were evident in the study. The rats showed improved visuo-spatial performance and better memory function. Dopamine, one of the most important neurotransmitters in the brain, is partly or entirely responsible for alertness, motivation, memory retention, learning, and mood, among many other cognitive functions. 9-Me-BC can slow down the reabsorption of dopamine by your neurons, increasing the total amount of dopamine available in the brain, thereby boosting focus, motivation, mood and learning ability. It is important to note that there are still no extensive human trials on 9-Me-BC and no conclusive evidence of its safety or effectiveness in humans. Before you take the drug, consult your doctor. Does 9-me-bc boost dopamine?9-me-bc acts as a dopamine reuptake inhibitor. This means it slows or completely prevents the reabsorption of dopamine by your synapses after the neurotransmitter has transmitted its “message”. This means there is more dopamine activating neuronal receptors for longer. In practical terms, the results of this are increased motivation, greater mental clarity, and improved mood. Benefits of 9 Me-BC9-MeBC offers a variety of benefits. Some of these include: Promots wakefulnessIndividuals who take 9-MeBC experience increased wakefulness. This is a common feature of nootropics and 9-Me-BC is no exception. It may be helpful for people who have excessive daytime sleepiness and want to remain awake throughout the day. Alertness increases9-MeBC improves alertness by increasing brain dopamine levels. The brain’s dopamine levels at any given time are linked to alertness, mood, wake-sleep cycles, and alertness. It improves your moodDopamine levels can influence mood, as we have already mentioned. People who have tried this nootropic say they feel more productive and alert after using it. Improves memory functionThe trials in rats showed that 9-MeBC improves spatial learning. The compound was administered to Thar rats for 10 days. They completed mazes faster than normal. This shows the effect of the drug on their learning capacity. Euphoria increasesDopamine levels high in dopamine can promote happiness, pleasure and satisfaction. People who take 9-MeBC may feel more motivated to work. It is important to note that 9-MeBC’s benefits are not supported by any substantial research. They are merely anecdotal. Before you start treatment with this drug, consult your doctor. Can 9-Me-BC help with Parkinson’s?There has been some recent clinical research on 9-me-bc as a potential treatment or combination therapy for Parkinson’s Disease. Knowing that 9-me-bc likely acts as a dopamine reuptake inhibitor, this makes sense; many accepted treatments for Parkinson’s disease work by raising dopamine levels throughout the brain or in parts most associated with the condition. Interestingly, in one study, researchers noted several different ways in which 9-me-bc may help with the progression of Parkinson’s disease:
Obviously, more work is needed before anyone concludes that 9-me-bc can help with Parkinson’s. Dosage Guide for 9-MeBCProperly taking drugs is essential for their effectiveness without side effects. At the time of writing, however, there was no established dosage guide. Users recommend that you take 1 capsule daily with plenty of water. Side effects may be more likely if you take more capsules. The powdered version of the drug has not yet been prescribed. To avoid severe side effects, do not take this medication without first consulting your doctor. Warnings and Side EffectsSide effects are a part of all drugs, including 9-MeBC. It is still quite new in the nootropic world and is under-researched so there is not much information on its potential negative side effects. These are some of the side effects associated with smart drugs. There is a chance that 9-MeBC could have similar effects. These include:
Side effects that can be more serious include depression, hallucinations and rashes. This is often due to incorrect use of the drug. 9-me-bc DNA damage?Does 9-me-bc cause DNA damage? This is, unfortunately, a real possibility. β-carboline alkaloids are very efficient photosynthesizers, and 9-me-bc is particularly efficient compared to other β-carboline alkaloids. This means that these compounds may cause DNA damage in cells when exposed to UVA radiation, which is the majority of the radiation in sunlight. We strongly recommend staying out of the sun as much as possible if you are going to use 9-me-bc. Where can you buy 9-MeBC online?9-MeBC can be purchased online by many online drug sellers. This is good news but it is important to be aware of the risks. Fake sellers sell counterfeit medications. The only way to ensure you get high-quality medication is to order them from trusted online pharmacies. At this moment, there is no 9-Me BC vendor. ViaBestBuys.com or CialisBit.com can be trusted vendors to source modafinil and armodafinil if you are looking for safer and more effective options. The Verdict: Complete 9-MeBC Review9-MeBC is a cognitive-enhancing drug that may be effective at improving a range of cognitive functions and measures of brain health. However, it is not recommended to purchase and use as it is still understudied, at least when compared to the likes of Modafinil and Fasoracetam. If you are looking for a compound to help you be more productive, mentally sharper and a more efficient learner, then we strongly recommend using a comprehensive nootropic stack. A natural nootropic stack is much better suited to long-term daily use than research chemicals like 9-me-bc and they can be just as effective, if not more so! Via https://www.vagarights.com/9-me-bc/ PRL-8-53 is another research chemical that we’ve received numerous questions about in recent months. Like most research compounds, PRL-8-53 does not have a very larg euser base. But also like other research chemicals, people that do use PRL-8-53 tend to be huge advocates of the drug. According to its fans – and manufacturers – this nootropic smart drug is a broad spectrum cognitive enhancer. They claim that it works by enhancing neurochemical production in the brain, specifically in relation to the catecholamine neurotransmitters dopamine and serotonin (plus acetylcholine). If it is really effective at boosting these three neurotransmitters without causing side effects, then it is likely that PRL-8-53 is one of the best cognitive enhancers in existence. In this article, we’re going to look at PRL-8-53 reviews, benefits, uses, and side effects to see if this nootropic compound is worth using or not. If you have any personal experience using PRL-8-53 please share it with us in the comments at the end. What is PRL-853?PRL-853 (Reference) is an artificial nootropic that’s derived from benzoic and phenylethylamine. Benzoic acids can be found in foods such as dairy products, fruits and vegetables. PRL-8-53’s drug name is methyl 2-benzyl-methyl amino ethylbenzoate. It is a promising addition that Dr. Nikolaus Hansl from Creighton University developed in 1972. Rumors and some documents suggested that Dr. Hansl (PRL-8-147) also created a stronger PRL-8-53. In 1978 Dr. Hansl did a study on humans that showed that volunteers could double their memory by taking one dose of the drug. PRL-8-53 was the first nootropic to be discovered. It is even described by Neurohackers as a powerful supplement that improves memory retention, recall, and memory formation. Methyl 3 2 benzyl is a brain supplement that causes changes in thinking and processing information. Its chemical composition protects brain cells from injury and prevents them developing neurological diseases. Cognitive function is better, which means that mental faculties such as intelligence, attention, alertness, and memory work at their best. How does PRL-8-53 Work?3-2-benzyl methyl amino ethyl benzoate or PRL-8-53 regulates neurotransmitters. According to Dr. Hansl it increases dopamine, modifies serotonin and enhances Acetylcholine activity. Acetylcholine, a neurotransmitter, works to improve memory. The increased levels of dopamine can make you more active, focused, and motivated. Serotonin is responsible for feelings of anxiety, depression, and difficulty sleeping. PRL 8 53 (53*8) blocks serotonin production in order to prevent these unproductive states. The lone research predicted that volunteers would develop impulsive and aggressive disorders due to dopamine or serotonin activity. These side effects weren’t common among them. Effects, Uses and BenefitsNootropics are used to improve cognition. PRL-853 reviews showed that it could enhance mental abilities within a short time. The effects and benefits of this supplement have not been fully researched. This claim is supported by anecdotal evidence. Its ability to increase cognitive function and mental ability is attested to by users. These are the main benefits of PRL-853. Long-term memory enhancementEvidence was found that participants received a dose of 5mg of PRL-853 two hours prior to a memorization test in the only human clinical study. The students listened to 12 words in different sequences. After the test was over, they were required to remember the words. They were again asked to recall the words after the test for 2 hours and 96hrs. These three cases showed that immediate recall did not provide any benefits over PRL-8-53. However, the results of the final test showed an improvement of 80%. Improved visuo-spatial memoryDr. Hansl’s unpublished research shows that volunteers were tested by recalling the geometric patterns shown to them. They did this by drawing them on a piece paper. The test shows high statistical data that support improved visual memory function following the PRL-853 supplement. Fluency in verbal communicationAnother test result is yet to be discovered. Participants were asked to create words using dots or letters. The drug’s potential for verbal fluency is further bolstered by higher scores among those on PRL-853. Other potential benefits of the drug include chemical effects in the brain that may provide additional benefits. These are the results of animal clinical trials. These same events are believed to occur in the human brain. Dopamine upregulationAs we age, our dopamine production decreases. This has a major impact on cognition. This compound regulates dopamine production, which helps to prevent cognitive decline and age-related cognitive decline. Memory formation over the long-termThe drug increased noradrenaline levels in animals when tested. It is possible to increase long-term storage by observing the same effect in humans. Enhances the cholinergic systemThe drug increases the brain’s acetylcholine level. This means that the drug can increase memory storage and retrieval. PRL-8-53 DosagePRL-8-53 is not yet approved for use in clinical trials. What is easily available in the amount that has been proven to have benefits for users? According to the published study, 5 mg is recommended. The effects of the drug can lead to subjects increasing their daily intake to 10-20mg depending on how they feel. The patent information outlines the ideal PRL-853 dosage. The dosage is proportional to body weight at.1-4 mg/kg. This ratio is controversial because it allows for a large range of dosage variations. How to take PRL-8-53There is no evidence that the drug can be taken in excess. It was however, proved lethal in animal testing. Although the powder supplement can be taken in many other ways, Dr. Hansl recommends that you take it orally. PRL-8-53 is usually available in powder jars of 1-5 grams. It can be taken by mouth, added to drinks, or in caps. Side EffectsPRL-8-53 is an easily tolerated nootropic that has not been tested in a large clinical study. It is possible that it will have side effects similar to other nootropics, if it does. Some users may experience mild headaches while taking the drug. There is no other reported side effect. Motor function was reduced in animals. This has yet to be tested on humans. You should begin with low doses, and gradually increase your intake depending on your body’s response. Reddit: Reviews and Experiences
These are some PRL-8-53 Reddit stories. According to inmy325xy “I started with very small amounts and gradually increased my intake. I feel 10mg is a good daily dose. It didn’t seem that 15mg was any better than 10. For Neuroscience testing, I tried 20mg and was amazed at the improvement in recall. “ According to baliflipper PRL has helped me increase my verbal fluency. It’s great for studying when combined with caffeine. It must be used in conjunction with studying and the exam to recall. “ According to wave78 “I combined PRL with Semax and caffeine and was able to memorize 300 questions for an exam in less than 3 hours. This combination was incredible for memory. By the way, I have terrible memories. I am not young. I also drank heavily for most of my adult life. You know me well, memory is not something I enjoy. It is saved for special occasions. ” This review will provide more information about the research and how you can buy PRL. Stacking PRL-8-53Nootropics work together. Each one has its own benefit, so stacking them correctly can have positive effects on the body. We don’t know enough about PRL-853 to be able to fully understand its benefits. However, we can still trust the idea that stacked supplements offer maximum benefits when combined. Why not stack PRL-8-53 and other supplements?A “stack” is a combination of multiple nootropics. Cognitive enhancers often stack ingredients to increase their effectiveness. Anecdotal evidence suggests that a stack might work well with these:
These supplements have been tested by users only and are not based upon research. These substances do not interact with PRL-853 in any way. Where can I buy PRL-853 Powder and CapsulesTrustworthy vendors should sell experimental drugs. It is not regulated and any vendor can claim that their products are authentic. SwissChems, a trusted nootropic vendor, offers lab-tested supplements so that customers can be sure of its purity. Customers are assured that the shipping methods will be used correctly so that they don’t have to worry about having to ship from faraway locations. PRL-8-53 powder can be purchased in 500mg jars. FAQsIs PRL-8-53 a nootropic?PRL-8-53 is a potent nootropic with a broad range of effects and more than one mechanism of action relating to cognitive performance. Does PRL-8-53 cause euphoria?A number of people have reported feeling a subtle wave of euphoria after taking PRL-8-53. This feeling of euphoria usually doesn’t last long and is typically mild. PRL-8-53 does not get you high like other psychoactive substances. Can you take PRL-8-53 with Adderall?There has been no clinical study looking at the combined use of PRL-8-53 and Adderall. It is highly likely that PRL-8-53 interacts with Adderall and other ADHD medications because it acts as a dopamine booster. Can you take PRL-8-53 with Modafinil?As is the case with Adderall and other ADHD medications, it is highly likely that PRL-8-53 interacts strongly with Modafinil. PRL-8-53 increases dopamine levels in the brain, which is also how Modafinil works. Via https://www.vagarights.com/prl-8-53/ NSI-189 is not exactly a widely used nootropic. However, if you’ve spent any time on Reddit (specifically r/nootropics), then you’ll know that the small percentage of people who use NSI-189 are generally huge fans of the compound. However, there is actually very little information out there on NSI-189, its benefits, how it works, or why anyone would want to use it. In this article, we’re going to look at NSI-189 in more detail to tell you everything you need to know about this fascinating nootropic compound. We’ll cover user reviews, side effects, where to buy, and the main mechanisms of action. We’ll also compare NSI-189 to other nootropics. If you have experience using NSI-189, please let us know in the comments! What is NSI-189?NSI-189, an experimental neurogenic compound, may be used to treat MDD, traumatic brain injuries, stroke, cognition issues, mental disorders, posttraumatic stress disorder and neurodegenerative diseases due to aging. Neuralstem Inc, a biopharmaceutical firm that develops NSI-199, is Neuralstem Inc. This chemical is being studied as an alternative drug for patients who have not responded to traditional medications. The phase I clinical trials were completed by 41 volunteers in 2011 (Reference). The phase IB trial, which was conducted in 2012 and 2014, focused on the treatment of patients with MDD. The phase II clinical trial, however, was not as successful than phase I. It did not meet the primary efficacy endpoint of MDD (Reference). NSI189 is currently being evaluated for other conditions, such as better brain health, stroke, diabetic neuropathy and neurodegenerative diseases, Angelman syndrome, and post-traumatic stress disorder. It is used to treat trauma brain injury. FDA granted NSI189 Orphan Drug Designation to treat Angelman syndrome, a rare condition. The study included patient recruitment as well as NSI imaging. NSI189, like all antidepressants, increases hippocampal volume. Its ability to screen rodents for compounds that cause the increase is what makes it stand out. Its ability to increase hippocampal volume, despite not being tested in humans, makes it an effective treatment for depression. Mechanism of Action: How does NSI-189 work?
NSI-189 could promote neurogenesis in the hippocampus derived neural stem cell. It may also affect the parts that are responsible for memory, learning, and emotion. This is in addition to other processes. The drug is a benzylpiperazine-aminopyridine that may pass the blood-brain barrier. Neurogenesis is stimulated by the hippocampal slices. This includes the left side of a human brain. It may also increase Ki67 or MAP2 in some cases (e.g. after stroke). It can also improve BDNF, GDNF and VEGF. Similar activities can be seen on the Skp complex, Cullin and F-box complex. NSI-189 has a few additional mechanisms that could prove its effectiveness as a treatment for depression. NSI 189 in the brain increases the size of the hippocampal by 20% and modulates aldosterone receptors through improved glucocorticoid resistant. Other possible mechanisms include TRPV1 antagonist and norepinephrine-dopamine reuptake inhibitor with binding affinity. Benefits and EffectsTo prove that this nootropic is effective in treating mental disorders, a sufficient clinical trial must be done on humans. This NSI 189 review outlines the benefits of using the product starting with the first trial. Broadly speaing, NSI-189 is thought to have both procognitive and antidepressant benefits. It appears to both broadly improve cognitive performance while reducing anxiety and symptoms of depression. On Human Studies
On Animal StudiesSupplements have shown more benefits for humans.
Does NSI-189 work for ADHD?There is no reason to think that NSI-189 would be good for ADHD symptoms. As far as know (going off the latest clinical data), symptoms of ADHD are primarily the result of neurotransmitter imbalances in the brain. Specifically, ADHD appears to be characterised by issues with both dopamine and norepinephrine. We know this because medications which cause spikes in these neurotransmitters calm the ADHD brain. NSI-189 does not have any effect on these neurotransmitters, so it is unlikely to help ADHD. Dosage and how to take NSI-189For visible results, NSI supplements should only be taken in the recommended dosage. For starters, a dose of 40mg is recommended. It can be taken one, twice, or three times a day for 28-days, depending on how the body reacts to it, according to a clinical trial that was focused on major depressive disorder (MDD) and neurodegenerative diseases. To avoid any adverse reactions, you should consult your doctor before taking the drug or other supplements. Side EffectsIs NSI-189 safe? The majority of clinical research on NSI 189 has been done on animals. Very few studies have been conducted on humans. However, side effects can be reported by patients in small doses or greater. Patients who take 40 mg of the drug may experience dry mouth, sleeplessness, headaches, dizziness and hyperthermia. High doses of the drug have not been associated with any long-term side effect. NSI-189 Reviews & Shared Experiences on RedditDespite the inability to conduct a sufficient clinical trial on humans, the phosphate compound was made available for human consumption. This is what users get from using NSI 189. According elasticoder: It has been working for me for over a month, along with consistent exercise and taking vitamins. The results have been amazing, I can’t believe it. Every morning, I add 40 mg to my coffee or orange juice. Within 15 minutes, you will start to feel the effects. You will feel stimulated, motivated and energized at first. It’s similar to Adderall, but more intense and healthier. The best thing about NSI189 is that you can stop taking it at any time. This compound is difficult to find. I was able to locate a legitimate vendor that had signed lab reports. You can check out their site ->https://science.bio/. “ According falre1028us “Personally, NSI-189 has been very helpful to me. I take 50mg of NSI-189 once daily in the morning. I feel a calm wave, improved long-term memory, as well as a significantly improved vision. “ According To ThechanceW: “So, I began taking NSI189 a little over a month ago, freebase from science.bio…The initial day, I took 40mg sublingually in my morning to very little effect… The next and third days, I did the exact same thing, but with no results. I noticed a slight lift in my mood the fourth day when I took 40mg of it with water. I have taken 80 to 110mg orally every morning since the fifth day, and on all subsequent days. I feel like I’ve been brought back into life. “ NSI-189 Freebase vs. Phosphate Powder – What’s the Difference?Sometimes, both freebase or phosphate may be available. Users can get confused and lose track of which one they should get. Both can improve their cognitive function and depressive symptoms. To help you understand the differences, here are some things to consider. PhosphateNeuralstem Inc uses phosphate in its clinical trials. It can be taken orally, and it is approximately 15 to 20% more costly than the other versions. However, it is more stable and has better bioavailability. FreebaseSublingual ROA is done with the freebase version. It is the secondary amino, a nitrogen atom that has been bonded to two carbon and one hydrogen atoms. It is not bioavailable. You might want to think about the following factors before you decide to purchase NSI 189. Where can I buy NSI-189 phosphate powder?Because of its rarity, it is difficult to find NSI 189 to buy. Even if there is NSI 189 for sale, you still need to verify that the vendor you choose is trustworthy and that the product you are purchasing is legal. Some compounds and supplements are very expensive, while others are too cheap. To avoid problems with NSI189, purchase from trusted sources.
Organoleptic verification can be a powerful method to identify compounds. If the online reports match, this method allows you to observe the chemical’s physical properties and appearance. Organoleptic verification is often based on appearance, taste, or smell. A chemical can be crystallized, have a faint odor, and taste bitter. NSI-189 has a lower density than other chemicals. 50mg of the supplement is equivalent in volume to a 0.15cc scoop. This dose is commonly used to treat patients suffering from depressive symptoms and cognition problems. The 40-120 mg NSI189 dosage may be used in a clinical trial. Editor’s Review: NSI-189 personal experience
Conclusion: Is NSI-189 worth using?NSI-189 is a fascinating nootropic. It has some really interesting mechanisms of action, and it is not thought to pose any serious side effect or long-term health risks. The compound clearly has both antidepressant and procognitive benefits, with few downsides (that we can tell from the scientific evidence so far). However, it must be said that NSI-189 has not been extensively studied in large-scale human clinical trials. A lot of the evidence we have is from rodent studies. We also think there are better options out there than NSI-189 for people who are looking for total brain optimization. If your goal is top-to-bottom, long-term, all-in-one cognitive enhancement and brain health protection, we recommend using a comprehensive nootropic stack. Via https://www.vagarights.com/nsi-189/ Oroxylin A, also known as Sabroxy(r), a promising nootropic with a history that dates back to approximately 5,000 years. This compound has been used in ancient healing practices for many benefits. However, researchers are only beginning to investigate its effects on neurological health, and it is now being investigated as one of the most effective nootropic compounds. With several culture and animal studies, we’re learning that oroxylin may exhibit the neurological-enhancing functions that Western research has been searching for. What is it? What is it? This article will explain what oroxylin A is, how it can impact brain function, how it works, as well as why the ancient benefits of this compound may be just what you need to be more productive and happier in the modern world. What is Oroxylin A?Oroxylin A, also known as Oroxylum Indicum, is a medicinal compound derived from the Indian trumpet tree. The tree can be found in tropical climates like India, Sri Lanka and Japan. It has been used in traditional medicine practices such as Ayurveda for thousands of years. The Indian trumpet tree was used to treat diarrhea, ulcers, fever and jaundice in ancient India. Recent research has shown that the active constituents of this plant may possess anti-inflammatory, antiulcerative, antioxidant and antiarthritic properties. Evidence suggests that oroxylin A, an active compound, may be a nootropic and enhance cognitive function. Oroxylin A’s Potential Cognitive BenefitsCurrently, the majority of research on oroxylin-A is animal or lab studies. What investigators have discovered so far suggests a strong neuro-supportive role for oroxylin A in the human mind. There are many interesting areas where researchers are investigating potential therapeutic uses for Oroxylin A:
Potential Impact on Attention DisordersOroxylin A was shown to increase ADD and ADHD behavior in animals. It also affects dopamine uptake. The dopamine system is a key indicator of ADHD and ADD. In one study, rats given oroxylin A showed improvement in attention and impulsivity due to enhanced dopamine neurotransmission.[4] May improve memoryResearchers gave mice drug-induced amnesia (memory impairment) to test the effects of oroxylin A on memory. They found that memory-impaired mice who took oroxylin were able to reverse cognitive impairments. The mice were able to escape successfully from training trials and showed improvements in their swimming skills and distances. The medical community is increasingly concerned about chemotherapy-induced cognitive impairment (also known as “chemo brain”). Patients who undergo chemotherapy experience an increase in oxidative Stress and potential dysfunction to their cells’ powerhouse, the mitochondria. Researchers gave mice oroxylin-A and chemotherapy in an animal study to evaluate the effects on brain function and brain health. After four weeks of treatment, researchers found that oroxylin A had prevented cancer-induced changes in oxidative and mitochondrial stress, as well as improved mitochondrial function in mice’s brains. Oroxylin also significantly inhibited chemotherapy-induced cognitive impairment during performance tests. [6] May increase Brain-Derived Neurotrophic Factor (BDNF)BDNF, a protein that plays an important role in neuroplasticity of the brain. It is involved in brain changes that affect learning and memory, and helps to maintain brain cells. Researchers found that oroxylin A could upregulate BDNF expression in neuronal cells. This was confirmed by a test tube study. [8] Anti-inflammatory actionMany chronic neurological diseases are linked to inflammation in the brain. Many of the diseases that we see in the West today are actually caused by inflammation. The Indian trumpet tree was used as an ayurvedic remedy called “Dasamoola” in India. It is a powerful anti-inflammatory formula. [9] Research has shown that oroxylin A, which comes from the Indian trumpet tree may be helpful in calming inflammation in osteoarthritis and rheumatoid joint pain. [10] [11] Preliminary evidence also suggests that oroxylin A may be beneficial in reducing inflammation in the brain, which is linked to Alzheimer’s. [12] Anti-oxidantThe brain’s excessive production of free radicals is one of the main causes of neurodegeneration. This can be seen in common diseases such as Parkinson’s and Alzhemier. [13] Oroxylin A has been shown to have antioxidant properties. Oroxylin A also has an antioxidant function, according to research. Oroxylin A Side EffectsThere are no known adverse effects or long-term side effects of Oroxylin A use. However, this is more a result of a lack of human clinical trials than the inherent safety of the nootropic. Most of the scientific studies looking at Oroxylin A have been rodent studies. Using mice does give us a rough indication of a compounds safety and toxicity, but it doesn’t translate exactly to humans and is unlikely to pick up on milder side effects that do not necessarily have external symptoms. That said, the main mechanism of action of Oroxylin A – raising BDNF levels in the brain – is unlikely to cause any notable negative side effects. We cannot recommend using a nootropic that hs not been thoroughly tested on humans in large scale, double-blind, placebo-controlled trials. What is Sabroxy?: Our ReviewThose of you looking into Oroxylin A more than likely came across it first as Sabroxy. This is a branded, standardized form of extract prepared from the dried bark of the Indian trumpet tree (Oroxylum indicum), containing a minimum of 10% Oroxylin A. Sabroxy is sold over the counter as a nootropic. Is Sabroxy a stimulant?Yes, Sabroxy is a central nervous system stimulant. Like methylphenidate and other stimulant drugs, Sabroxy works by acting as a dopamine reuptake inhibitor and a negative allosteric modulator of the benzodiazepine site of the GABAa receptor. This makes it a stimulant, and a psychoactive stimulant at that. Is Sabroxy Safe?A study was carried out to evaluate the safety of Sabroxy® administration to the liver of the mice. Male C57BL/6J mice were administered with powdered food mixed with Sabroxy (500mg/kg/day) for 4 weeks. After the treatment period, the possibility of hepatotoxicity was assessed by assaying the hepatic health markers in the serum and by liver histology. The results showed that Sabroxy did not affect the total body weight of the mice after 4 weeks of treatment period. Sabroxy treatment also did not alter the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin, albumin, globulin and total protein. Perhaps most importantly, Sabroxy did not affect the liver histology. In this and other studies like it, Sabroxy (or Oroxylin A) was found to be safe upto 500mg/kg/day. Is Oroxylin A a good nootropic?On balance, we don’t think Oroxylin A (or Sabroxy) is really worth taking. There simply haven’t been enough studies done on Sabroxy to be absolutely certain of its efficacy as a cognitive enhancer. What’s more, there are other, more reliable nootropics for raising BDNF than Oroxylin A. Via https://www.vagarights.com/oroxylin-a/ We have been asked to review Selank now by several readers. This was a bit of a surprise to us as we saw Selank as quite a niche nootropic with relatively few users. But clearly Selank users are growing in number, and there is a dearth of information regarding Selank’s side effects, benefits, costs, and uses. There are a few resources out there for people wanting to learn about Selank. A number of websites now list it as one of the best nootropics for anxiety, while some individuals have said that it is one of the most effective natural supplements for raising BDNF levels in the brain. In this article, we’re going to try and tell you everything you need to know about the nootropic Selank, how to use it, and whether you should! If you have any experiences with Selank, please post your review in the comments. What is Selank?Selank is a peptide medication that was developed by the Institute of Molecular Genetics of The Russian Academy of Sciences. It mimics many of the effects of human tuftsin by being a synthetic analog. Selank is known to affect the expression of Interleukin-6, (IL-6), and the balance of T-helper cell cytokines. Selank has been shown to affect monoamine neurotransmitters’ levels and instigate serotonin metabolism . Selank was found to increase the expression of brain-derived neural factor (BDNF), in the hippocampuss of rats [2]. BDNF, a protein that supports the survival of neurons and promotes growth and differentiation of new cells, is a protein. It is abundant in the hippocampus region, which is responsible for learning and memory. Selank’s ability increase BDNF levels may indicate that it may improve cognitive function and memory. It is a heptapeptide with a molecular mass of 751.887 g*mol-1 and has the following sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). Numerous animal studies have been done to examine the effects of Selank’s on anxiety, depression, and cognition. One study showed that Selank could decrease depression-like behavior among rats [3] What is Selank’s Effect on the Brain?Selank, a peptide drug, has a variety of effects on nerve cells. Selank may function by modulating the GABAergic system [4]. Selank could also be acting through other systems such as the serotonergic and dopaminergic systems. This is why Selank exhibits similar physiological effects to classical benzodiazepines. Selank’s antidepressant and anxiolytic effects are very similar to those of benzodiazepines. However, it doesn’t seem to interact in the same manner with GABA receptors. Selank does not appear to have side effects like tolerance and abuse potential, which can be common with benzodiazepines. What are the Benefits of Selank for Cognition?Selank’s ability to boost brain levels of BDNF can explain the cognitive benefits it offers. BDNF, a protein that promotes neuron growth and keeps neurons alive, is a protein. The hippocampus is where BDNF is most abundant. It is responsible for learning and memory. Selank has been shown that the GABAergic system plays a role in cognition. Other potential benefits of Selank’s cognition are:
Selank vs Semax: Which is better?What’s the difference between Selank and Semax? Many people compare these nootropic compounds directly because they have somewhat overlapping effects. But can you say if one is better than the other? Selank and Semax are very different compounds with different structures, different chemical formulas and different effects. Yes there is some overlap, but one cannot be said to be “better” than the other because they have an overall different effect on cognitive performance. To put it simply, Selank is more anxiolytic, while Semax is more stimulating and motivational. For the treatment or reduction of anxiety symptoms, stress, strokes, and depression disorders, Selank could be the better choice, while Semax is better placed to treat certain medical conditions that benefit from stimulant use. Selank Online – Where to Buy?You may be curious about where to buy Selank online. Selank is not FDA-approved, so it may be difficult to find in the United States. You can find Selank replicas at a few locations. Selank Reviews: What do people think about Selank on Reddit?Reddit has many glowing reviews about Selank. Selank users report better sleep quality and clearer thinking. Side effects like anxiety or headaches have been reported by some users. However, these side effects are usually mild and disappear after a few days. Take a look below at what people have to say about Selank on Reddit: Selank is now day three and I’m really enjoying it. It’s great for cognitive enhancements. I use it in combination with Sunifiram and Noopept. Selank is a great tool that I’ve used for several weeks. I felt a little anxious at first, but it disappeared after one week. I am sleeping much better and my thinking is clearer Selank is my favorite nootropic. I’ve tried many, but Selank is my favourite. It has helped me to reduce anxiety and stress, and improved my memory and focus. How do you take Selank for Cognitive Enhancement?Selank is a peptide which is sprayed into your nose in a sitting position. It is recommended that you clean the nasal passage after applying the drug. The nasal mucosa should not be touched. Selank should be taken with an empty stomach, either in the morning or after-work. Selank can be taken upto three times daily. Selank should be taken every day for at least 2 weeks to achieve cognitive enhancement. It is not necessary to cycle, but some people might choose to after long periods of use. What is the Recommended Dosage for Selank?Selank should be taken 200-300 micrograms (micrograms) three times daily. If necessary, the recommended daily dosage can be increased to 400 mg three times per day. Selank is usually administered as a 0.15 mg spray. This equates to 75 mg/spray, or approximately 149 pounds for an adult who weighs 67kg. Selank can be administered in 75 mg doses. This means that you will need to take approximately 2 to 3 sprays per day spread over a total of 675 mg. Selank’s most frequent side effects are:
There are also some less frequently reported side effects of Selank, which include:
Selank should be stopped if any of these side effects persist, or worsen. Selank WithdrawalsSelank has a similar mechanism of action to some traditional anxiety medications. This leads many people to assume that Selank use is followed by withdrawals or a “comedown”. However, clinical studies show no serious side effects from Selank use, including withdrawals. Simply put, Selank has no sedating or negative cognitive side effects and has no associated addiction or withdrawal problems. What Nootropics are Similar to Selank?Selank is not the only nootropic that has brain effects similar to Selank. These include:
In terms of brain effects, all three of these nootropics have similar effects to Selank. All three of these nootropics improve cognitive function, decrease anxiety, and improve mood. Review Conclusion: Should you use Selank?Our Editor, Brian Johnson, used Selank for 2 weeks to try this nootropic out. Here is his personal review:
Via https://www.vagarights.com/selank/ |
About UsVAGA is an artists collective dedicated to improving mental health and fighting cognitive decline through art therapy. The organisation brings together artists, clinicians and academic psychologists to foster research collaboration and the development of new art therapies. ArchivesNo Archives Categories |